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KMID : 0359320060460020165
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Korean Journal of Veterinary Research
2006 Volume.46 No. 2 p.165 ~ p.169
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Diagnosis of pemphigus erythematosus in a Jindo dog
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방동하
최을수/김민규/최은화/정윤찬/강민수/김대용/황철용/이창우/윤화영
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Abstract
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A 6-year-old female Jindo dog weighing 20 kg was presented to the Veterinary Medical Teaching Hospital of Seoul National University for the formation of crust and erosion of the nasal bridge and planum, and for alopecia of ear margin. Erythema, crusts, alopecia and erosions were present in the nasal planum and the bridge of the nose on physical examination. There were no abnormalities on CBC, serum chemistry, and basic dermatologic examination which included skin scraping, bacterial cultures, and fungal cultures. On cytology, the acantholytic cells were surrounded by non-degenerate neutrophils. Biopsy samples obtained from skin lesionswere diagnosedpemphigus erythematosus by histopathology and immunochemical staining. Therefore the dog was initially treated with oral prednisolone as an immunosuppressive dose for tour weeks, but clinical manifestations did not improve so far.
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KEYWORD
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acantholytic cells, pemphigus erythematosus, prednisolone
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